What the Heck Is a Placebo Anyway? | Mother Jones

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Why fake medicine can make you feel better.

Anton Mesmer, an 18th-century German physician, believed a mysterious force he called “animal magnetism” could be used to cure people. Mesmer’s theory was that there was invisible fluid in the body that could be controlled by magnetized objects and that disease was a result of “obstacles” to those fluids’ flow. To fight the disease, Mesmer used hypnotic procedures on his patients. At times, he would give people water he had “mesmerized” in order to cure them.

While Mesmer claimed some success with patients, he had critics. One was Benjamin Franklin, who saw Mesmer’s healing techniques for what they were: placebos. In modern medicine, a placebo is a fake medical treatment used to test out the results of real medications. The placebo effect is, essentially, the body’s response (in some instances, a very real response) to this fake treatment. In other words, Mesmer’s medications weren’t scientifically sound, but they may have made patients feel better through the power of suggestion.

Award-winning science writer Erik Vance has spent a lot of time thinking about the placebo effect. In his book, Suggestible You: The Curious Science of Your Brain’s Ability to Deceive, Transform, and Heal, Vance explores placebos, hypnosis, and how beliefs influence bodily responses to pain. “Placebos and beliefs generally is so much a part of our lives,” he tells Kishore Hari on a recent episode of the Inquiring Minds podcast. “It has an amazing power to change our bodies.”


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Vance has a unique perspective on the topic: He was raised in a Christian Science household and saw a doctor for the first time when he was 18 years old. “Belief was basically my health care,” he says.

Today, placebos are used by researchers to test whether drugs are actually effective in treating medical conditions—that is, whether patients who are taking an experimental medication see better results than patients who just think they are taking one. For some conditions—Parkinson’s disease, for instance—placebos can actually be an effective treatment.

It’s hard to figure out what the precise mechanisms of the placebo effect are and how they work. But as Vance explains, we now know that they often involve real chemicals produced by the body—real drugs from your “internal pharmacy.” Some of these chemicals are used by the brain to make sure that…

What the Heck Is a Placebo Anyway? | Mother Jones

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